Optimize clinical trials with speech-based behavioural biomarkers

Accelerate trial timelines, improve retention, and enhance behavioural insights with semantic speech analysis powered by AI.

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A clinical trial with 1000 patients may cost roughly 1.5M$/week

Precision screening of study population, detection of psychoemotive changes and catching early signals of treatment effectiveness helps to optimize trials.

Subtle shifts in speech, behaviour, and emotion appear weeks before traditional clinical scales respond.

But many trials still miss these critical behavioural endpoints, relying instead on infrequent visits and recall-based self-reporting.

We leverage speech-based biomarkers to detect treatment effects earlier and more precisely

Our AI analyses speech and voice samples to track real-time behavioral change, improving data quality, retention, and trial outcomes.

Why they matter

Digital biomarkers can cut clinical trial timelines by 10–30% and save $5–25 million per trial

Improved trial integrity and patient retention

Predicts trial fitness, early disengagement and dropout risks

Supports proactive retention strategies to maintain trial power

Improves retention by 5–10%, avoiding re-recruitment

Estimated savings

$1M–5M per Phase II/III trial

Faster detection of 
treatment effects

Detects cognitive, mood, and  behavioural changes weeks earlier than traditional scales

Enables earlier interim decisions and shorter trial durations

Potential to reduce trial timelines by 2–6 months

Estimated savings

$5M–20M per trial

More precise and sensitive 
endpoints

Provides continuous, objective behavioural data with comparability

Enables optimising study population and earlier detection of efficacy

Strengthens regulatory packages for faster approvals and label extension to differentiate

Estimated savings

Upside from earlier market access: $10M–50M+

Expertise

Unique AI Driven methodology for deploying behavioral markers and psychometric scales

Programmable
AI Agent

Agentic AI and guided journaling to extract natural speech data​

GenAI powered conversational AI for natural discussions (voice or text)

Curated guided journaling  programs to support trial monitoring​

Feedback based on behavioural data​

Behavioural biomarkers
BxE:32
Surprise
bxPS:03
Low self-efficacy
BxE:04
Dissapproval
BxE:32
Surprise
bxPS:03
Low self-efficacy
BxE:04
Dissapproval
BxPS:12
Lack of social support
BxTS:05
Defensive
BxE:23
Apprehension
BxPS:12
Lack of social support
BxTS:05
Defensive
BxE:23
Apprehension
BxTS:04
Disappointed
BxP5:05
Expressing vulnerability
BxTS:05
Defensive
BxTS:04
Disappointed
BxP5:05
Expressing vulnerability
BxTS:05
Defensive
BxPS:12
Lack of social support
BxE:04
Disapproval
BxE:32
Surprise
BxPS:12
Lack of social support
BxE:04
Disapproval
BxE:32
Surprise
BxE:32
Surprise
bxPS:03
Low self-efficacy
BxE:04
Dissapproval
BxE:32
Surprise
bxPS:03
Low self-efficacy
BxE:04
Dissapproval

Behavioral marker
detection

Behavioural & emotional speech biomarkers for personalised insights​

Psychosocial expressions and behaviours

​Emotion detection applying Plutchik’s classification model

Paralinguistic, e.g., speech rate, length of phrases, interruptions, pauses​

Automated clinical scales

Proprietary AI algorithms for automating clinical psychometric assessments​

Analysing patient sessions, interviews and journal entries with custom LLMs for correspondence to psychometric scales​

Psychometric progress analytics following individual's behaviour over time ​

All-in-one platform

The Behavioural Intelligence Platform for Modern Clinical Trials

Built to capture, analyse, and translate speech into real-time behavioural insight.

Our AI-powered behavioral analytics platform delivers continuous, low-burden monitoring of emotional, behavioral and cognitive change through natural voice.

Patient App

Low-friction voice journaling with guided prompts. Keeps patients engaged while collecting high-quality speech data in real time.

Trial Dashboard

Real-time behavioural insights for clinical teams. Monitor trends, receive alerts, and track engagement across cohorts.

Biomarker Builder

Create and validate custom speech-based endpoints. Design new behavioural biomarkers tailored to your study protocol or therapeutic area.

Developer API

Possibility to integrate into existing trial infrastructures.

Expertise

We deeply understand the problem space and master the technology to resolve it

picture of Katarina Cantell

Dr. Katarina Cantell

Founder & CEO

Katarina has over 20 years of experience in building solutions for digital and IT services, healthcare, and sports technology (wearables), with a specialisation in digital biomarkers. Her academic background is in behavioural sciences and information systems.

picture of Riko Nyberg

Riko Nyberg

Chief Technology Officer

Riko is one of the world-leading experts developing NLP-based AI systems. Riko has previously worked at Apple on Siri speech solutions, built the AI core at Vainu, and digital solutions for SLUSH. He has also worked at the Stanford University Behaviour Design Lab. Riko is a tech-team lead with full-stack experience and emphasis on backend, AI/ML, NLP, speech technology and GenAI.

picture of Marcel Verboom

Marcel Verboom

Interim CCO

Marcel is Adalyon's commercial advisor with background leading Google’s VC and Private Equity partnerships in Northern Europe. He brings along 15+ years of experience in Sales, Business Development, Partnerships, Growth Marketing, and International Expansions. He has a drive for developing high performing teams, combined with a deep affinity for meaningful new technologies and data.

picture of Krista Kauppi

Dr. Krista Kauppi

Chief Operating Officer

Krista is a strong product and operations executive managing development and partnerships. She has previously led product teams and automated health analytics. She has experience in clinical health and wellbeing metrics, as well as facilitating and operating clinical trials in biotechnology.

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Herman Smith

Chief Architect

With over 20 years of experience in building scalable, fault-tolerant solutions, Herman is a Cloud Software Architect and Engineer mastering the full solution stack at Adalyon. He has experience from global enterprises and technology startups and has previously developed advanced analytics and blockchain technologies in fintech.

Ruben Marin

Senior mobile developer

After around 20 years as a software developer—15 of them fully focused on Apple technologies—Ruben is a senior mobile developer. He holds a degree in Telecommunications and has extensive experience helping tech startups’ mobile apps thrive in highly competitive markets, with a special focus on Finland. His passion is working on transformative projects that positively impact people’s lives.

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Darja Husu

Customer Success Manager

Darja is a Behavioural Scientist and Customer Success Manager. Darja holds a Master's degree in Social Sciences from the University of Helsinki, specialising in business anthropology and organisational psychology. She is also working on service and product development. Darja’s character is a unique combination of fearless ambition and authentic humanity.

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Anna Salmela

Data Engineer

Anna works with data analytics and AI development. She is passionate about NLP and machine learning with solid hands-on experience in working with language and text data. Anna holds a Masters’ degree in Digital Language Studies from the University of Turku, with her second degree in Computer Science on it’s way. She is a problem-solver aspiring to make a difference for human wellbeing.

picture of Kane Bidwell

Dr. Kane Bidwell

Advisor, Organisational Psychology,
Director of Psychology at Egon Zehnder

Kane is the Director of Psychology at Egon Zehnder, a global leadership advisory and executive recruitment firm. He has a background in organisational psychology and enjoys creating new solutions combining AI and organisational psychology. Kane has extensive, international experience in organisational development, leadership assessments, and radar on the international HR tech market.

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